Study about the Effect of choline inositol on PCOS disease in Iraqi women

Abstract

Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age and is characterized by hormonal imbalances, menstrual irregularities, and metabolic dysfunction. This study aimed to evaluate the effectiveness of Choline Inositol supplementation in improving hormonal and metabolic profiles in Iraqi women diagnosed with PCOS. The research problem focused on the lack of effective, low-risk treatments to manage PCOS symptoms and improve quality of life.An observational, comparative, cross-sectional study design was used. Ninety women aged 18–40 years were divided into three groups: healthy controls, untreated PCOS patients, and PCOS patients treated with Choline Inositol (1000 mg twice daily for three months). FSH, LH, testosterone and prolactin were determined by ELISA and chemiluminescence immunoassays for hormones. BMI and ultrasound were used to evaluate the metabolic and ovarian alterations. The findings indicated a significant increase in BMI, LH, testosterone, and prolactin and a significant decrease in FSH levels in untreated PCOS patients in comparison with healthy ones.

Patients treated with Choline inositol improved in all aspects including reduction of BMI and testosterone levels, normalization of LH/FSH ratio and finally abatement of menstrual irregularity.It is concluded that Choline Inositol has a positive effect on hormonal and metabolic aspects of PCOS. So, tossing in supplements actually looked like it helped with ovulation, toned down those wild androgen levels, and maybe even nudged weight in the right direction for folks with PCOS. Feels like a pretty solid extra tool in the PCOS toolbox, honestly. Still, gotta say—we seriously need bigger, better studies before anyone starts popping pills left and right or changing up the whole treatment game. Science likes receipts.